{"id":411,"date":"2025-08-15T06:54:50","date_gmt":"2025-08-15T06:54:50","guid":{"rendered":"https:\/\/lwfzyzmd.com\/product\/%e9%98%bf%e5%b8%83%e6%98%94%e6%9b%bf%e5%b0%bc-%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%9712%e5%b2%81%e5%8f%8a%e4%bb%a5%e4%b8%8a%e6%82%a3%e6%9c%89%e9%9a%be%e6%b2%bb%e6%80%a7-%e4%b8%ad%e5%ba%a6%e8%87%b3\/"},"modified":"2026-09-23T00:37:33","modified_gmt":"2026-09-22T17:37:33","slug":"%e9%98%bf%e5%b8%83%e6%98%94%e6%9b%bf%e5%b0%bc-%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%9712%e5%b2%81%e5%8f%8a%e4%bb%a5%e4%b8%8a%e6%82%a3%e6%9c%89%e9%9a%be%e6%b2%bb%e6%80%a7-%e4%b8%ad%e5%ba%a6%e8%87%b3","status":"publish","type":"product","link":"https:\/\/lwfzyzmd.com\/th\/product\/%e9%98%bf%e5%b8%83%e6%98%94%e6%9b%bf%e5%b0%bc-%e7%94%a8%e4%ba%8e%e6%b2%bb%e7%96%9712%e5%b2%81%e5%8f%8a%e4%bb%a5%e4%b8%8a%e6%82%a3%e6%9c%89%e9%9a%be%e6%b2%bb%e6%80%a7-%e4%b8%ad%e5%ba%a6%e8%87%b3\/","title":{"rendered":"Lucius LuciAbro Abrocitinib 100mg"},"content":{"rendered":"

\u963f\u5e03\u6614\u66ff\u5c3c\u8bf4\u660e\u4e66<\/strong><\/p>\n

\u5546\u54c1\u540d\u79f0\uff1aLuciAbro<\/p>\n

\u751f\u4ea7\u5546\uff1a\u5362\u4fee\u65af\u5236\u836f Lucius<\/p>\n

\u4e2d\u6587\u540d\u79f0\uff1a\u963f\u5e03\u6614\u66ff\u5c3c<\/p>\n

\u82f1\u6587\u540d\u79f0\uff1aAbrocitinib<\/p>\n

\u836f\u54c1\u6279\u51c6\u6587\u53f7\uff1a02 L 1061\/24<\/p>\n

 <\/p>\n

 <\/p>\n

\u3010\u6982\u62ec\u3011<\/strong><\/p>\n

\u963f\u5e03\u6614\u66ff\u5c3c\u662f\u4e00\u79cdJanus\u6fc0\u9176\uff08JAK\uff09\u6291\u5236\u5242\u3002<\/p>\n

\u963f\u5e03\u6614\u66ff\u5c3c\u901a\u8fc7\u963b\u65ad\u4e09\u78f7\u9178\u817a\u82f7\uff08ATP\uff09\u7ed3\u5408\u4f4d\u70b9\u53ef\u9006\u5730\u6291\u5236JAK1\u3002\u5728\u65e0\u7ec6\u80de\u5206\u79bb\u9176\u8bd5\u9a8c\u4e2d\uff0c\u963f\u5e03\u6614\u66ff\u5c3c\u5bf9JAK1\u7684\u9009\u62e9\u6027\u9ad8\u4e8eJAK2\uff0828\u500d\uff09\u3001JAK3\uff08\u5927\u4e8e340\u500d\uff09\u3001\u916a\u6c28\u9178\u6fc0\u9176\uff08TYK\uff092\uff0843\u500d\uff09\uff0c\u4ee5\u53ca\u66f4\u5e7f\u6cdb\u7684\u57fa\u8bfa\u7ec4\u3002\u76ee\u524d\u5c1a\u4e0d\u6e05\u695a\u6291\u5236\u7279\u5b9aJAK\u9176\u4e0e\u6cbb\u7597\u6548\u679c\u7684\u76f8\u5173\u6027\u3002\u6bcd\u4f53\u5316\u5408\u7269\u548c\u6d3b\u6027\u4ee3\u8c22\u7269\u5728\u4f53\u5916\u4ee5\u76f8\u4f3c\u7684\u9009\u62e9\u6027\u6c34\u5e73\u6291\u5236JAK1\u6d3b\u6027\u3002<\/p>\n

 <\/p>\n

\u3010\u9002\u5e94\u75c7\u3011<\/strong><\/p>\n

\u7528\u4e8e\u6cbb\u759712\u5c81\u53ca\u4ee5\u4e0a\u60a3\u6709\u96be\u6cbb\u6027\u3001\u4e2d\u5ea6\u81f3\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u7684\u6210\u4eba\u548c\u513f\u7ae5\u60a3\u8005\uff0c\u8fd9\u4e9b\u60a3\u8005\u7684\u75be\u75c5\u4e0d\u80fd\u7528\u5176\u4ed6\u5168\u8eab\u6027\u836f\u7269(\u5305\u62ec\u751f\u7269\u5236\u54c1)\u5145\u5206\u63a7\u5236\uff0c\u6216\u8005\u4e0d\u5efa\u8bae\u4f7f\u7528\u8fd9\u4e9b\u7597\u6cd5\u3002<\/p>\n

 <\/p>\n

\u3010\u89c4\u683c\u3011\u00a0\u00a0<\/strong><\/p>\n

100mg\/\u7247\uff0c14\u7247\/\u74f6\u3002<\/p>\n

 <\/p>\n

\u3010\u8d2e\u5b58\u3011<\/strong><\/p>\n

\u8d2e\u5b58\u4e8e20\u00b0C \uff5e25\u00b0C (68\u00b0C \uff5e77\u00b0F)\uff1b\u5141\u8bb8\u8303\u56f4\u4e3a15\uff5e30\u00b0C (59\u201386\u00b0F)\u6e29\u5ea6\u6761\u4ef6\u4e0b\u77ed\u9014\u8fd0\u8f93\u3002<\/p>\n

 <\/p>\n

\u3010\u7528\u6cd5\u7528\u91cf\u3011<\/strong><\/p>\n

1\u3001\u6bcf\u65e5\u53e3\u670d\u4e00\u6b21\uff0c\u6bcf\u6b21100mg\uff0c\u5982\u679c\u6ca1\u6709\u53cd\u5e94\uff0c\u5219\u589e\u52a0\u5230\u6bcf\u6b21200 mg\u3002<\/p>\n

2\u3001\u4e2d\u5ea6\u80be\u529f\u80fd\u635f\u5bb3\u7684\u60a3\u8005:\u6bcf\u65e5\u53e3\u670d\u4e00\u6b21\uff0c\u6bcf\u6b2150mg\uff0c\u5982\u679c\u6ca1\u6709\u53cd\u5e94\uff0c\u5219\u589e\u52a0\u5230\u6bcf\u6b21100 mg\u3002<\/p>\n

3\u3001CYP2C19 \u4ee3\u8c22\u4e0d\u826f\u7684\u60a3\u8005:\u6bcf\u65e5\u53e3\u670d\u4e00\u6b21\uff0c\u6bcf\u6b2150mg\uff0c\u5982\u679c\u6ca1\u6709\u53cd\u5e94\uff0c\u5219\u589e\u52a0\u5230\u6bcf\u6b21100 mg\u3002<\/p>\n

 <\/p>\n

\u3010\u7528\u836f\u7981\u5fcc\u3011<\/strong><\/p>\n

\u5728\u6cbb\u7597\u7684\u524d3\u4e2a\u6708\uff0c\u9664\u5c0f\u5242\u91cf\u963f\u53f8\u5339\u6797\u5916\uff0c\u670d\u7528\u6297\u8840\u5c0f\u677f\u6cbb\u7597\u7684\u60a3\u8005\u7981\u7528Abrocitinib(\u226481mg\/\u5929\uff09\u3002<\/p>\n

 <\/p>\n

\u3010\u4e0d\u826f\u53cd\u5e94\u3011<\/strong><\/p>\n

\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94(\u2265\u670d\u7528100 mg\u548c200 mg\u7684\u53d7\u8bd5\u8005\u4e2d\u76841%\uff09\u5305\u62ec\uff1a\u9f3b\u54bd\u708e\u3001\u6076\u5fc3\u3001\u5934\u75db\u3001\u5355\u7eaf\u75b1\u75b9\u3001\u8840\u808c\u9150\u78f7\u9178\u6fc0\u9176\u5347\u9ad8\u3001\u5934\u6655\u3001\u5c3f\u8def\u611f\u67d3\u3001\u75b2\u52b3\u3001\u75e4\u75ae\u3001\u5455\u5410\u3001\u53e3\u54bd\u75bc\u75db\u3001\u6d41\u611f\u3001\u80c3\u80a0\u708e\u3002<\/p>\n

\u6700\u5e38\u89c1\u7684\u4e0d\u826f\u53cd\u5e94(\u2265\u63a5\u53d7100mg\u6216200mg\u836f\u7269\u6cbb\u7597\u7684\u53d7\u8bd5\u8005\u4e2d\u76841%\uff09\u8fd8\u5305\u62ec\uff1a\u8113\u75b1\u75c5\u3001\u9ad8\u8840\u538b\u3001\u63a5\u89e6\u6027\u76ae\u708e\u3001\u4e0a\u8179\u75db\u3001\u8179\u90e8\u4e0d\u9002\u3001\u5e26\u72b6\u75b1\u75b9\u548c\u8840\u5c0f\u677f\u51cf\u5c11\u75c7\u3002<\/p>\n

 <\/p>\n

\u3010\u6ce8\u610f\u4e8b\u9879\u3011<\/strong><\/p>\n

1.\u4e25\u91cd\u611f\u67d3\uff1a<\/p>\n

\u5728\u4f7f\u7528Abrocitinib\u6cbb\u7597\u7279\u5e94\u6027\u76ae\u708e\u7684\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u6700\u5e38\u89c1\u7684\u4e25\u91cd\u611f\u67d3\u662f\u5355\u7eaf\u75b1\u75b9\u3001\u5e26\u72b6\u75b1\u75b9\u548c\u80ba\u708e\u3002\u5728\u63a5\u53d7\u7528\u4e8e\u6cbb\u7597\u708e\u75c7\u7684JAK\u6291\u5236\u5242\u7684\u60a3\u8005\u4e2d\uff0c\u51fa\u73b0\u4e86\u5bfc\u81f4\u4f4f\u9662\u6216\u6b7b\u4ea1\u7684\u4e25\u91cd\u611f\u67d3\uff0c\u5305\u62ec\u7ed3\u6838\u75c5\u548c\u7ec6\u83cc\u3001\u4fb5\u88ad\u6027\u771f\u83cc\u3001\u75c5\u6bd2\u548c\u5176\u4ed6\u673a\u4f1a\u6027\u611f\u67d3\u3002\u907f\u514d\u5728\u6d3b\u52a8\u6027\u4e25\u91cd\u611f\u67d3\uff08\u5305\u62ec\u5c40\u90e8\u611f\u67d3\uff09\u60a3\u8005\u4e2d\u4f7f\u7528Abrocitinib\u3002\u8003\u8651\u60a3\u8005\u5728\u5f00\u59cbAbrocitinib\u524d\u6cbb\u7597\u7684\u98ce\u9669\u548c\u76ca\u5904\uff1a<\/p>\n

\u2022\u60a3\u6709\u6162\u6027\u6216\u590d\u53d1\u6027\u611f\u67d3<\/p>\n

\u2022\u66fe\u63a5\u89e6\u8fc7\u7ed3\u6838\u75c5\u7684\u4eba<\/p>\n

\u2022\u6709\u4e25\u91cd\u6216\u75c5\u53f2\u7684\u60a3\u8005\u673a\u4f1a\u6027\u611f\u67d3<\/p>\n

\u2022\u66fe\u5728\u5730\u65b9\u6027\u80ba\u7ed3\u6838\u6216\u5730\u65b9\u6027\u771f\u83cc\u75c5\u5730\u533a\u5c45\u4f4f\u6216\u65c5\u884c<\/p>\n

\u2022\u6709\u53ef\u80fd\u5bfc\u81f4\u611f\u67d3\u7684\u6f5c\u5728\u6761\u4ef6<\/p>\n

\u5728\u4f7f\u7528Abrocitinib\u6cbb\u7597\u671f\u95f4\u548c\u6cbb\u7597\u540e\uff0c\u5bc6\u5207\u76d1\u6d4b\u60a3\u8005\u611f\u67d3\u75c7\u72b6\u548c\u4f53\u5f81\u7684\u53d1\u5c55\u3002\u5982\u679c\u60a3\u8005\u51fa\u73b0\u4e25\u91cd\u6216\u673a\u4f1a\u6027\u611f\u67d3\uff0c\u505c\u6b62Abrocitinib\u3002\u542f\u52a8\u5b8c\u6574\u7684\u8bca\u65ad\u6d4b\u8bd5\u548c\u9002\u5f53\u7684\u6297\u83cc\u6cbb\u7597\u3002\u5728\u4f7f\u7528Abrocitinib\u91cd\u65b0\u5f00\u59cb\u6cbb\u7597\u4e4b\u524d\uff0c\u5e94\u4ed4\u7ec6\u8003\u8651\u4f7f\u7528Abrocitinib\u6cbb\u7597\u7684\u98ce\u9669\u548c\u76ca\u5904\u3002<\/p>\n

\uff081\uff09\u80ba\u7ed3\u6838\uff1b\u7ed3\u6838\u75c5<\/p>\n

\u5728\u5f00\u59cbAbrocitinib\u6cbb\u7597\u4e4b\u524d\u8bc4\u4f30\u548c\u6d4b\u8bd5\u7ed3\u6838\u75c5\u60a3\u8005\uff0c\u5e76\u8003\u8651\u6bcf\u5e74\u5728\u7ed3\u6838\u75c5\u9ad8\u6d41\u884c\u5730\u533a\u5bf9\u60a3\u8005\u8fdb\u884c\u7b5b\u67e5\u3002Abrocitinib\u4e0d\u5efa\u8bae\u7528\u4e8e\u6d3b\u52a8\u6027\u7ed3\u6838\u75c5\u60a3\u8005\u3002\u5bf9\u4e8e\u65b0\u8bca\u65ad\u4e3a\u6f5c\u4f0f\u6027\u80ba\u7ed3\u6838\u6216\u4e4b\u524d\u672a\u7ecf\u6cbb\u7597\u7684\u6f5c\u4f0f\u6027\u80ba\u7ed3\u6838\u60a3\u8005\uff0c\u6216\u6f5c\u4f0f\u6027\u80ba\u7ed3\u6838\u68c0\u6d4b\u9634\u6027\u4f46\u80ba\u7ed3\u6838\u611f\u67d3\u98ce\u9669\u9ad8\u7684\u60a3\u8005\uff0c\u5728\u5f00\u59cbAbrocitinib\u4e4b\u524d\u5f00\u59cb\u5bf9\u6f5c\u4f0f\u6027\u80ba\u7ed3\u6838\u8fdb\u884c\u9884\u9632\u6027\u6cbb\u7597\u3002\u76d1\u6d4b\u60a3\u8005\u662f\u5426\u51fa\u73b0\u7ed3\u6838\u75c5\u7684\u75c7\u72b6\u548c\u4f53\u5f81\uff0c\u5305\u62ec\u5728\u5f00\u59cb\u6cbb\u7597\u524d\u68c0\u6d4b\u4e3a\u6f5c\u4f0f\u6027\u7ed3\u6838\u75c5\u611f\u67d3\u9634\u6027\u7684\u60a3\u8005\u3002<\/p>\n

\uff082\uff09\u75c5\u6bd2\u518d\u6fc0\u6d3b<\/p>\n

Abrocitinib\u7684\u4e34\u5e8a\u7814\u7a76\u62a5\u544a\u4e86\u75c5\u6bd2\u518d\u6fc0\u6d3b\uff0c\u5305\u62ec\u75b1\u75b9\u75c5\u6bd2\u518d\u6fc0\u6d3b\uff08\u5982\u5e26\u72b6\u75b1\u75b9\u3001\u5355\u7eaf\u75b1\u75b9\uff09\u3002\u5982\u679c\u75c5\u4eba\u51fa\u73b0\u5e26\u72b6\u75b1\u75b9\uff0c\u8003\u8651\u4e2d\u65adAbrocitinib\u76f4\u5230\u53d1\u4f5c\u3002\u636e\u62a5\u9053\uff0c\u5728\u63a5\u53d7JAK\u6291\u5236\u5242\u7684\u60a3\u8005\u4e2d\uff0c\u4e59\u578b\u809d\u708e\u75c5\u6bd2\uff08HBV\uff09\u91cd\u65b0\u6fc0\u6d3b\u3002\u5728\u5f00\u59cb\u6cbb\u7597\u524d\u548c\u4f7f\u7528Abrocitinib\u6cbb\u7597\u671f\u95f4\uff0c\u6839\u636e\u4e34\u5e8a\u6307\u5357\u8fdb\u884c\u75c5\u6bd2\u6027\u809d\u708e\u7b5b\u67e5\u548c\u76d1\u6d4b\u662f\u5426\u518d\u6b21\u6fc0\u6d3b\u3002Abrocitinib\u4e0d\u5efa\u8bae\u7528\u4e8e\u6d3b\u52a8\u6027\u4e59\u578b\u809d\u708e\u6216\u4e19\u578b\u809d\u708e\u60a3\u8005[\u89c1\u4e34\u5e8a\u836f\u7406\u5b66\uff0812.3\uff09]\u3002\u5728\u4f7f\u7528Abrocitinib\u6cbb\u7597\u671f\u95f4\uff0c\u76d1\u6d4b\u975e\u6d3b\u52a8\u6027HBV\u60a3\u8005\u7684HBV DNA\u8868\u8fbe\u3002\u5982\u679c\u5728\u4f7f\u7528Abrocitinib\u6cbb\u7597\u671f\u95f4\u68c0\u6d4b\u5230HBV DNA\uff0c\u8bf7\u54a8\u8be2\u809d\u810f\u4e13\u5bb6\u3002<\/p>\n

2.\u6b7b\u4ea1\u7387<\/p>\n

\u5728\u53e6\u4e00\u79cdJAK\u6291\u5236\u5242\u5bf9\u81f3\u5c11\u6709\u4e00\u79cd\u5fc3\u8840\u7ba1\u5371\u9669\u56e0\u7d20\u768450\u5c81\u53ca\u4ee5\u4e0a\u7c7b\u98ce\u6e7f\u6027\u5173\u8282\u708e\uff08RA\uff09\u60a3\u8005\u7684\u5927\u89c4\u6a21\u968f\u673a\u4e0a\u5e02\u540e\u5b89\u5168\u6027\u7814\u7a76\u4e2d\uff0c\u89c2\u5bdf\u5230\u4e0eTNF\u963b\u6ede\u5242\u76f8\u6bd4\uff0c\u4f7f\u7528JAK\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u7684\u5168\u56e0\u6b7b\u4ea1\u7387\u66f4\u9ad8\uff0c\u5305\u62ec\u5fc3\u8840\u7ba1\u731d\u6b7b\u3002Abrocitinib\u672a\u88ab\u6279\u51c6\u7528\u4e8eRA\u3002\u8003\u8651\u4e2a\u4f53\u60a3\u8005\u5728\u5f00\u59cb\u6216\u7ee7\u7eed\u6cbb\u7597Abrocitinib\u4e4b\u524d\u7684\u76ca\u5904\u548c\u98ce\u9669\u3002<\/p>\n

3. \u6076\u6027\u80bf\u7624\u548c\u6dcb\u5df4\u589e\u751f\u6027\u75be\u75c5<\/p>\n

\u5728\u4f7f\u7528Abrocitinib\u6cbb\u7597\u7279\u5e94\u6027\u76ae\u708e\u7684\u4e34\u5e8a\u7814\u7a76\u4e2d\u89c2\u5bdf\u5230\u6076\u6027\u80bf\u7624\uff0c\u5305\u62ec\u975e\u9ed1\u8272\u7d20\u7624\u76ae\u80a4\u764c\uff08NMSC\uff09\u3002\u5bf9\u76ae\u80a4\u764c\u98ce\u9669\u589e\u52a0\u7684\u60a3\u8005\u8fdb\u884c\u5b9a\u671f\u76ae\u80a4\u68c0\u67e5\u3002\u5e94\u901a\u8fc7\u7a7f\u9632\u62a4\u670d\u548c\u4f7f\u7528\u5e7f\u8c31\u9632\u6652\u971c\u6765\u9650\u5236\u66b4\u9732\u5728\u9633\u5149\u548c\u7d2b\u5916\u7ebf\u4e0b\u3002<\/p>\n

\u6076\u6027\u80bf\u7624\uff0c\u5305\u62ec\u6dcb\u5df4\u7624\uff0c\u53d1\u751f\u5728\u63a5\u53d7JAK\u6291\u5236\u5242\u6cbb\u7597\u708e\u75c7\u7684\u60a3\u8005\u8eab\u4e0a\u3002\u5728\u4e00\u9879\u9488\u5bf9RA\u60a3\u8005\u7684\u53e6\u4e00\u79cdJAK\u6291\u5236\u5242\u7684\u5927\u89c4\u6a21\u3001\u968f\u673a\u3001\u4e0a\u5e02\u540e\u5b89\u5168\u6027\u7814\u7a76\u4e2d\uff0c\u4e0eTNF\u963b\u6ede\u5242\u6cbb\u7597\u7684\u60a3\u8005\u76f8\u6bd4\uff0c\u4f7f\u7528JAK\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u6076\u6027\u80bf\u7624\u53d1\u751f\u7387\uff08\u4e0d\u5305\u62ec\u975e\u9ed1\u8272\u7d20\u7624\u76ae\u80a4\u764c\uff08NMSC\uff09\uff09\u66f4\u9ad8\u3002Abrocitinib\u672a\u88ab\u6279\u51c6\u7528\u4e8eRA\u3002\u4e0eTNF\u963b\u6ede\u5242\u6cbb\u7597\u7684\u60a3\u8005\u76f8\u6bd4\uff0cJAK\u6291\u5236\u5242\u6cbb\u7597\u7684\u60a3\u8005\u6dcb\u5df4\u7624\u53d1\u751f\u7387\u66f4\u9ad8\u3002\u4e0eTNF\u963b\u6ede\u5242\u6cbb\u7597\u7684\u5438\u70df\u8005\u76f8\u6bd4\uff0c\u76ee\u524d\u6216\u8fc7\u53bb\u63a5\u53d7JAK\u6291\u5236\u5242\u6cbb\u7597\u7684\u5438\u70df\u8005\u80ba\u764c\u53d1\u751f\u7387\u66f4\u9ad8\u3002\u5728\u8fd9\u9879\u7814\u7a76\u4e2d\uff0c\u73b0\u5728\u6216\u8fc7\u53bb\u7684\u5438\u70df\u8005\u60a3\u6076\u6027\u80bf\u7624\u7684\u98ce\u9669\u589e\u52a0\u3002<\/p>\n

\u8003\u8651\u4e2a\u4f53\u60a3\u8005\u5728\u5f00\u59cb\u6216\u7ee7\u7eed\u7528Abrocitinib\u6cbb\u7597\u4e4b\u524d\u7684\u76ca\u5904\u548c\u98ce\u9669\uff0c\u7279\u522b\u662f\u5728\u5df2\u77e5\u6076\u6027\u80bf\u7624\uff08\u975e\u6210\u529f\u6cbb\u7597\u7684NMSC\uff09\u7684\u60a3\u8005\u4e2d\uff0c\u5728\u6cbb\u7597\u65f6\u53d1\u751f\u6076\u6027\u80bf\u7624\u7684\u60a3\u8005\uff0c\u4ee5\u53ca\u5f53\u524d\u6216\u8fc7\u53bb\u5438\u70df\u8005\u7684\u60a3\u8005\u3002<\/p>\n

4. \u4e3b\u8981\u5fc3\u8840\u7ba1\u4e0d\u826f\u4e8b\u4ef6<\/p>\n

Abrocitinib\u6cbb\u7597\u7279\u5e94\u6027\u76ae\u708e\u7684\u4e34\u5e8a\u7814\u7a76\u62a5\u544a\u4e86\u4e3b\u8981\u7684\u5fc3\u8840\u7ba1\u4e0d\u826f\u4e8b\u4ef6\u3002\u5728\u4e00\u9879\u9488\u5bf9\u53e6\u4e00\u79cdJAK\u6291\u5236\u5242\u7684\u5927\u578b\u3001\u968f\u673a\u3001\u4e0a\u5e02\u540e\u5b89\u5168\u6027\u7814\u7a76\u4e2d\uff0c\u4e0e\u4f7f\u7528TNF\u963b\u6ede\u5242\u6cbb\u7597\u7684RA\u60a3\u8005\u76f8\u6bd4\uff0c\u4f7f\u7528JAK\u6291\u5236\u5242\u6cbb\u759750\u5c81\u53ca\u4ee5\u4e0a\u4e14\u81f3\u5c11\u6709\u4e00\u79cd\u5fc3\u8840\u7ba1\u98ce\u9669\u56e0\u7d20\u7684RA\u60a3\u8005\uff0c\u5176\u4e3b\u8981\u4e0d\u826f\u5fc3\u8840\u7ba1\u4e8b\u4ef6\uff08MACE\uff09\u7684\u53d1\u751f\u7387\uff08\u5b9a\u4e49\u4e3a\u5fc3\u8840\u7ba1\u6b7b\u4ea1\u3001\u975e\u81f4\u547d\u6027\u5fc3\u808c\u6897\u6b7b\uff08MI\uff09\u548c\u975e\u81f4\u547d\u6027\u4e2d\u98ce\uff09\u66f4\u9ad8\u3002Abrocitinib\u672a\u88ab\u6279\u51c6\u7528\u4e8eRA\u3002\u76ee\u524d\u6216\u8fc7\u53bb\u5438\u70df\u8005\u7684\u98ce\u9669\u589e\u52a0\u3002\u8003\u8651\u4e2a\u4f53\u60a3\u8005\u5728\u5f00\u59cb\u6216\u7ee7\u7eed\u7528Abrocitinib\u6cbb\u7597\u4e4b\u524d\u7684\u76ca\u5904\u548c\u98ce\u9669\uff0c\u7279\u522b\u662f\u5728\u5f53\u524d\u6216\u8fc7\u53bb\u5438\u70df\u8005\u548c\u5176\u4ed6\u5fc3\u8840\u7ba1\u5371\u9669\u56e0\u7d20\u60a3\u8005\u4e2d\u3002\u5e94\u544a\u77e5\u60a3\u8005\u4e25\u91cd\u5fc3\u8840\u7ba1\u4e8b\u4ef6\u7684\u75c7\u72b6\u4ee5\u53ca\u53d1\u751f\u65f6\u91c7\u53d6\u7684\u63aa\u65bd\u3002\u5bf9\u4e8e\u7ecf\u5386\u8fc7\u5fc3\u808c\u6897\u6b7b\u6216\u4e2d\u98ce\u7684\u60a3\u8005\uff0c\u505c\u6b62\u670d\u7528Abrocitinib\u3002<\/p>\n

5. \u8840\u6813\u5f62\u6210<\/p>\n

\u5728\u7279\u5e94\u6027\u76ae\u708e\u7684\u4e34\u5e8a\u7814\u7a76\u4e2d\uff0c\u5728\u63a5\u53d7Abrocitinib\u6cbb\u7597\u7684\u60a3\u8005\u4e2d\u89c2\u5bdf\u5230\u6df1\u9759\u8109\u8840\u6813\u5f62\u6210\uff08DVT\uff09\u548c\u80ba\u6813\u585e\uff08PE\uff09\u3002\u636e\u62a5\u9053\uff0c\u5728\u63a5\u53d7\u7528\u4e8e\u6cbb\u7597\u708e\u75c7\u7684JAK\u6291\u5236\u5242\u7684\u60a3\u8005\u4e2d\uff0c\u8840\u6813\u5f62\u6210\uff0c\u5305\u62ecDVT\u3001PE\u548c\u52a8\u8109\u8840\u6813\u5f62\u6210\u3002\u8bb8\u591a\u4e0d\u826f\u53cd\u5e94\u90fd\u5f88\u4e25\u91cd\uff0c\u6709\u4e9b\u751a\u81f3\u5bfc\u81f4\u6b7b\u4ea1\u3002\u5728\u4e00\u9879\u9488\u5bf9\u53e6\u4e00\u79cdJAK\u6291\u5236\u5242\u7684\u5927\u578b\u3001\u968f\u673a\u3001\u4e0a\u5e02\u540e\u5b89\u5168\u6027\u7814\u7a76\u4e2d\uff0c\u4e0eTNF\u963b\u6ede\u5242\u6cbb\u7597\u7684RA\u60a3\u8005\u76f8\u6bd4\uff0c50\u5c81\u53ca\u4ee5\u4e0a\u4e14\u81f3\u5c11\u6709\u4e00\u79cd\u5fc3\u8840\u7ba1\u98ce\u9669\u56e0\u7d20\u7684RA\u60a3\u8005\u7684\u603b\u8840\u6813\u5f62\u6210\u3001DVT\u548cPE\u53d1\u751f\u7387\u66f4\u9ad8\u3002Abrocitinib\u672a\u88ab\u6279\u51c6\u7528\u4e8eRA\u3002\u907f\u514d\u5728\u8840\u6813\u5f62\u6210\u98ce\u9669\u589e\u52a0\u7684\u60a3\u8005\u4e2d\u4f7f\u7528Abrocitinib\u3002\u5982\u679c\u51fa\u73b0\u8840\u6813\u75c7\u72b6\uff0c\u505c\u6b62Abrocitinib\uff0c\u5e76\u5bf9\u60a3\u8005\u8fdb\u884c\u9002\u5f53\u7684\u8bc4\u4f30\u548c\u6cbb\u7597\u3002<\/p>\n

6. \u514d\u75ab<\/p>\n

\u5728\u5f00\u59cbAbrocitinib\u4e4b\u524d\uff0c\u6309\u7167\u5f53\u524d\u514d\u75ab\u6307\u5357\u7684\u5efa\u8bae\u5b8c\u6210\u6240\u6709\u9002\u9f84\u63a5\u79cd\uff0c\u5305\u62ec\u9884\u9632\u6027\u5e26\u72b6\u75b1\u75b9\u75ab\u82d7\u63a5\u79cd\u3002\u907f\u514d\u5728Abrocitinib\u6cbb\u7597\u524d\u3001\u6cbb\u7597\u671f\u95f4\u548c\u6cbb\u7597\u540e\u7acb\u5373\u63a5\u79cd\u6d3b\u75ab\u82d7\u3002<\/p>\n

 <\/p>\n

\u3010\u5b89\u5168\u4e0e\u7597\u6548\u3011<\/strong><\/p>\n

\u57283\u4e2a\u968f\u673a\u3001\u53cc\u76f2\u3001\u5bf9\u7167\u7ec4\u4e2d\u8bc4\u4f30\u4e86Abrocitinib\u4f5c\u4e3a\u5355\u4e00\u7597\u6cd5\u4ee5\u53ca\u4e0e\u80cc\u666f\u5c40\u90e8\u76ae\u8d28\u7c7b\u56fa\u9187\u8054\u5408\u4f7f\u7528\u7684\u7597\u6548\uff0c\u6839\u636e\u7814\u7a76\u8005\u7684\u6574\u4f53\u8bc4\u4f30\uff08IGA\uff09\u8bc4\u5206\uff0c\u5bf91615\u540d12\u5c81\u53ca\u4ee5\u4e0a\u7684\u4e2d\u91cd\u5ea6\u7279\u5e94\u6027\u76ae\u708e\u53d7\u8bd5\u8005\uff08Abrocitinib\u672a\u88ab\u6279\u51c6\u7528\u4e8e\u513f\u79d1\u60a3\u8005\uff09\u8fdb\u884c\u5b89\u6170\u5242\u5bf9\u7167\u8bd5\u9a8c[\u8bd5\u9a8c-AD-1\uff08NCT03349060\uff09\u3001\u8bd5\u9a8c-AD-2\uff08NCT03575871\uff09\u548c\u8bd5\u9a8c-AD-3\uff08NCT03720470\uff09]\u2265\u6e7f\u75b9\u9762\u79ef\u548c\u4e25\u91cd\u7a0b\u5ea6\u6307\u6570\uff08EASI\uff09\u8bc4\u5206\u226516.\u4f53\u8868\u9762\u79ef\uff08BSA\uff09\u53d7\u7d2f\u226510%\u548c\u7619\u75d2\u5cf0\u503c\u6570\u503c\u8bc4\u5b9a\u91cf\u8868\uff08PP-NRS\uff09\u22654\u968f\u673a\u5316\u524d\u7684\u57fa\u7ebf\u68c0\u67e5\u3002<\/p>\n

\u603b\u4f53\u800c\u8a00\uff0c53%\u7684\u53d7\u8bd5\u8005\u4e3a\u7537\u6027\uff0c69%\u7684\u53d7\u8bd5\u8005\u4e3a\u767d\u4eba\uff0c64%\u7684\u53d7\u8bd5\u8005\u7684\u57fa\u7ebfIGA\u5f97\u5206\u4e3a3\uff08\u4e2d\u5ea6AD\uff09\uff0c36%\u7684\u53d7\u8bd5\u8005\u7684\u57fa\u7ebfIGA\u5f97\u5206\u4e3a4\uff08\u91cd\u5ea6AD\uff09\u3002\u57fa\u7ebf\u5e73\u5747EASI\u5f97\u5206\u4e3a30\u5206\u3002\u57fa\u7ebf\u5e73\u5747\u5e74\u9f84\u4e3a36\u5c81\uff0c8%\u7684\u53d7\u8bd5\u800512\u5c81\u81f318\u5c81\u4ee5\u4e0b\uff0c92%\u7684\u53d7\u8bd5\u800518\u5c81\u6216\u4ee5\u4e0a\u3002\u8fd9\u4e9b\u8bd5\u9a8c\u4e2d\u7684\u53d7\u8bd5\u8005\u662f\u90a3\u4e9b\u5bf9\u4e4b\u524d\u7684\u5c40\u90e8\u6cbb\u7597\u53cd\u5e94\u4e0d\u8db3\u7684\u53d7\u8bd5\u8005\uff0c\u6216\u8005\u662f\u90a3\u4e9b\u5728\u533b\u5b66\u4e0a\u4e0d\u9002\u5b9c\u8fdb\u884c\u5c40\u90e8\u6cbb\u7597\u7684\u53d7\u8bd5\u8005\uff0c\u6216\u8005\u662f\u90a3\u4e9b\u63a5\u53d7\u8fc7\u5305\u62ec\u675c\u5339\u5355\u6297\u5728\u5185\u7684\u7cfb\u7edf\u6027\u6cbb\u7597\u7684\u53d7\u8bd5\u8005\u3002\u5728\u6bcf\u9879\u8bd5\u9a8c\u4e2d\uff0c\u8d85\u8fc740%\u7684\u53d7\u8bd5\u8005\u66fe\u63a5\u53d7\u8fc7\u5168\u8eab\u6cbb\u7597\u3002\u5728\u8bd5\u9a8c-AD-1\u548c\u8bd5\u9a8c-AD-2\u4e2d\uff0c6%\u7684\u53d7\u8bd5\u8005\u670d\u7528\u8fc7\u675c\u5339\u5355\u6297\uff0c\u800c\u5728\u8bd5\u9a8c-AD-3\u4e2d\uff0c\u4e8b\u5148\u4e0d\u5141\u8bb8\u4f7f\u7528\u675c\u5339\u5355\u6297\u3002<\/p>\n

\u7b2c2\u5468\u8fbe\u5230PP-NRS4\u7684\u53d7\u8bd5\u8005\u6bd4\u4f8b\uff08\u5b9a\u4e49\u4e3a\u2265\u4e0e\u5b89\u6170\u5242\uff08\u4e24\u4e2a\u8bd5\u9a8c\u4e2d\u5747\u4e3a2%\uff09\u76f8\u6bd4\uff0c\u670d\u7528Abrocitinib\u5355\u836f200mg\u6bcf\u65e5\u4e00\u6b21\uff08\u5728\u8bd5\u9a8c-AD-1\u4e2d\u4e3a28%\uff0c\u5728\u8bd5\u9a8c-AD-2\u4e2d\u4e3a24%\uff09\u548c100mg\u6bcf\u65e5\u4e00\u6b21\uff08\u5728\u4e24\u4e2a\u8bd5\u9a8c\u4e2d\u5747\u4e3a11%\uff09\u7684\u53d7\u8bd5\u8005\u7684PP-NRS\uff08PP-NRS\uff09\u8bc4\u5206\u6bd4\u57fa\u7ebf\u9ad84\u5206\u3002\u4e0e\u5b89\u6170\u5242\u7ec4\u76f8\u6bd4\uff0cAbrocitinib\u5355\u4e00\u7597\u6cd5\u7ec4\uff08\u6bcf\u65e5\u4e00\u6b21\uff0c100 mg\u6216200 mg\uff09\u7684\u53d7\u8bd5\u8005\u5728\u7b2c12\u5468\u7619\u75d2\u75c7\u72b6\u5f97\u5230\u6539\u5584\u7684\u6bd4\u4f8b\u66f4\u9ad8\u3002<\/p>\n

\u4e0e\u5b89\u6170\u5242\uff088%\uff09\u76f8\u6bd4\uff0c\u670d\u7528200 mg Abrocitinib\u6bcf\u65e5\u4e00\u6b21\uff0830%\uff09\u548c100 mg Abrocitinib\u6bcf\u65e5\u4e00\u6b21\uff0814%\uff09\u5e76\u7ed3\u5408\u80cc\u666f\u836f\u7269\u5c40\u90e8\u6cbb\u7597\u7684\u53d7\u8bd5\u8005\u5728\u7b2c2\u5468\u8fbe\u5230PP-NRS4\u7684\u6bd4\u4f8b\u66f4\u9ad8\u3002\u5728\u8bd5\u9a8c-AD-1\u3001\u8bd5\u9a8c-2\u548c\u8bd5\u9a8c-AD-3\u4e2d\uff0c\u5bf9\u5e74\u9f84\u3001\u6027\u522b\u3001\u79cd\u65cf\u3001\u4f53\u91cd\u548c\u4e4b\u524d\u7cfb\u7edf\u6027AD\u6cbb\u7597\u7684\u68c0\u67e5\u672a\u53d1\u73b0\u8fd9\u4e9b\u4e9a\u7ec4\u5bf9\u6bcf\u65e5\u4e00\u6b21100 mg\u6216200 mg Abrocitinib\u7684\u53cd\u5e94\u5b58\u5728\u5dee\u5f02\u3002<\/p>\n","protected":false},"excerpt":{"rendered":"

\u963f\u5e03\u6614\u66ff\u5c3c\u8bf4\u660e\u4e66 \u5546\u54c1\u540d\u79f0\uff1aLuciAbro \u751f\u4ea7\u5546\uff1a\u5362\u4fee\u65af\u5236\u836f Lucius \u4e2d\u6587\u540d\u79f0\uff1a\u963f\u5e03\u6614\u66ff\u5c3c \u82f1\u6587\u540d\u79f0 […]<\/p>\n","protected":false},"featured_media":696,"comment_status":"open","ping_status":"closed","template":"","meta":{"advanced_seo_description":"","jetpack_seo_html_title":"","jetpack_seo_noindex":false,"jetpack_seo_schema_type":""},"product_brand":[],"product_cat":[553],"product_tag":[],"class_list":["post-411","product","type-product","status-publish","has-post-thumbnail","product_cat-553","first","instock","sale","purchasable","product-type-simple"],"jetpack_sharing_enabled":true,"_links":{"self":[{"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/product\/411","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/comments?post=411"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/media\/696"}],"wp:attachment":[{"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/media?parent=411"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/product_brand?post=411"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/product_cat?post=411"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/lwfzyzmd.com\/th\/wp-json\/wp\/v2\/product_tag?post=411"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}