{"id":837,"date":"2025-08-15T06:56:33","date_gmt":"2025-08-15T06:56:33","guid":{"rendered":"https:\/\/lwfzyzmd.com\/product\/%e5%8a%b3%e6%8b%89%e6%9b%bf%e5%b0%bc-lorladx-lorlatinib-%e5%a4%8d%e5%88%b6\/"},"modified":"2026-09-23T01:37:24","modified_gmt":"2026-09-22T18:37:24","slug":"%e5%8a%b3%e6%8b%89%e6%9b%bf%e5%b0%bc-lorladx-lorlatinib","status":"publish","type":"product","link":"https:\/\/lwfzyzmd.com\/th\/product\/%e5%8a%b3%e6%8b%89%e6%9b%bf%e5%b0%bc-lorladx-lorlatinib\/","title":{"rendered":"Lao Big Bear BIGBEAAR LORLADX Lorlatinib 100mg"},"content":{"rendered":"<p>\u5382\u5bb6:\u8001\u631d\u5927\u718a\u5236\u836f<\/p>\n<p class=\"jianjie\">\u7b80\u4ecb\uff1a100mg*30\u7247<\/p>\n<p>\u52b3\u62c9\u66ff\u5c3c(lorlatinib)\u662f\u7b2c\u4e09\u4ee3\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c(non-small cell lung cancer,NSCLC)\u65b0\u836f,\u5177\u6709\u5bf9\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176(anaplastic lymphoma kinase,ALK)\u548cc-ros\u539f\u764c\u57fa\u56e01(c-ros oncogene 1,ROS1)\u53cc\u91cd\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176(receptor tyrosine kinase,RTK)\u5f3a\u6291\u5236\u4f5c\u7528,\u7528\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u8fc7\u81f3\u5c11\u4e00\u79cdALK\u6291\u5236\u836f\u6cbb\u7597,\u5982\u7b2c\u4e00\u4ee3ALK\u6291\u5236\u836f\u514b\u5511\u66ff\u5c3c(crizotinib)\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u63a8\u8350\u5242\u91cf\u3011<\/p>\n<p>\u2022 \u5b8c\u5168\u6309\u7167\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\u7684\u65b9\u5f0f\u670d\u7528 LORLADX\u3002 \u4e0d\u8981\u6539\u53d8\u5242\u91cf\u6216\u505c\u6b62\u670dLORLADX\uff0c\u9664\u975e\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\u8fd9\u6837\u505a\u3002<\/p>\n<p>\u2022 \u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u4f1a\u6539\u53d8\u60a8\u7684\u5242\u91cf\u3001\u6682\u65f6\u505c\u6b62\u6216\u6c38\u4e45\u505c\u6b62\u4f7f\u7528 LORLADX \u8fdb\u884c\u6cbb\u7597\u5982\u679c\u60a8\u51fa\u73b0\u526f\u4f5c\u7528\u3002<\/p>\n<p>\u2022 \u541e\u4e0b\u6574\u4e2a LORLADX \u836f\u7247\u3002 \u4e0d\u8981\u5480\u56bc\u3001\u538b\u788e\u6216\u5206\u5f00 LORLADX \u7247\u5242\u3002 \u4e0d\u8981\u670d\u7528 LORLADX\u5982\u679c\u836f\u7247\u7834\u635f\u3001\u7834\u88c2\u6216\u4e0d\u5b8c\u6574\u3002<\/p>\n<p>\u2022 \u6bcf\u5929\u5927\u7ea6\u5728\u540c\u4e00\u65f6\u95f4\u670d\u7528 LORLADX\u3002<\/p>\n<p>\u2022\u00a0\u60a8\u53ef\u4ee5\u968f\u9910\u6216\u5355\u72ec\u670d\u7528 LORLADX\u3002<\/p>\n<p>\u2022 \u5982\u679c\u60a8\u9519\u8fc7\u4e86\u5242\u91cf\uff0c\u8bf7\u5728\u8bb0\u8d77\u65f6\u5c3d\u5feb\u670d\u7528\u3002 \u4f46\u662f\uff0c\u5982\u679c\u5b83\u63a5\u8fd1\u60a8\u7684\u4e0b\u4e00\u6b21\u670d\u836f\u65f6\u95f4\uff08\u57284 \u5c0f\u65f6\uff09\uff0c\u53ea\u9700\u5728\u60a8\u7684\u5e38\u89c4\u65f6\u95f4\u670d\u7528\u4e0b\u4e00\u5242\u5373\u53ef\u3002<\/p>\n<p>\u2022 \u5982\u679c\u60a8\u5728\u670d\u7528\u4e00\u5242 LORLADX \u540e\u5455\u5410\uff0c\u8bf7\u52ff\u670d\u7528\u989d\u5916\u5242\u91cf\u3002 \u5728\u60a8\u7684\u5e38\u89c4\u65f6\u95f4\u670d\u7528\u4e0b\u4e00\u5242\u3002<\/p>\n<p>\u5382\u5bb6:\u8001\u631d\u5927\u718a\u5236\u836f<\/p>\n<p class=\"jianjie\">\u7b80\u4ecb\uff1a\u52b3\u62c9\u66ff\u5c3c\uff08lorlatinib\uff09\u662f\u7b2c\u4e09\u4ee3\u6cbb\u7597\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff08\u975e\u5c0f\u7ec6\u80de\u80ba\u764c\uff0cNSCLC\uff09\u65b0\u836f\uff0c\u5177\u6709\u5bf9\u95f4\u53d8\u6027\u72b6\u6001\u72b6\u6001\uff08\u95f4\u53d8\u6027\u6dcb\u5df4\u7624\u6fc0\u9176\uff0cALK\uff09\u548cc-ros\u539f\u764c\u57fa\u56e01(c-ros\u764c\u57fa\u56e01,ROS1)\u53cc\u91cd\u53d7\u4f53\u916a\u6c28\u9178(\u53d7\u4f53\u916a\u6c28\u9178\u6fc0\u9176\uff08RTK\uff09\u5f3a\u6291\u5236\u4f5c\u7528\uff0c\u5bf9\u4e8e\u6cbb\u7597\u65e2\u5f80\u63a5\u53d7\u81f3\u5c11\u4e00\u79cdALK\u6291\u5236\u836f\u6cbb\u7597\uff0c\u5982\u7b2c\u4e00\u4ee3ALK\u6291\u5236\u836f\u514b\u5511\u66ff\u5c3c\uff08\u514b\u5511\u66ff\u5c3c\uff09\u6216\u7b2c\u4e8c\u4ee3A&#8230;<\/p>\n<p>\u3010\u5546\u54c1\u540d\u79f0\u3011<\/p>\n<p>\u540d\u79f0\uff1a\u52b3\u62c9\u66ff\u5c3c<\/p>\n<p>\u4ea7\u54c1\u540d\u79f0\uff1aLORLLADX<\/p>\n<p>\u4e2d\u6587\u540d\u79f0\uff1a\u52b3\u62c9\u66ff\u5c3c\u7247<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u89c4\u683c\u3011<\/p>\n<p>100\u6beb\u514b<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u9002\u5e94\u75c7\u3011<\/p>\n<p>\u2022 \u7531\u5f02\u5e38\u7684\u95f4\u53d8\u6027\u505c\u6ede\uff08ALK\uff09\u57fa\u56e0\u5f15\u8d77\u7684\u6076\u75be<\/p>\n<p>\u2022 \u5df2\u7ecf\u6269\u6563\u5230\u60a8\u8eab\u4f53\u7684\u5176\u4ed6\u90e8\u4f4d<\/p>\n<p>\u2022 \u66fe\u670d\u7528\u827e\u4e50\u66ff\u5c3c\u6216\u8272\u745e\u66ff\u5c3c\u836f\u7269\uff0c\u6216\u540c\u65f6\u670d\u7528\u514b\u5511\u66ff\u5c3c\u836f\u7269\u548c\u81f3\u5c11\u4e00\u79cd\u5176\u4ed6\u836f\u7269\u6765\u6cbb\u7597\u7531 ALK \u57fa\u56e0\u5f15\u8d77\u7684\u975e\u5c0f\u7ec6\u80de\u80ba\u764c<\/p>\n<p>\u5c1a\u8282\u65e5LORLADX\u5bf9\u513f\u7ae5\u662f\u5426\u5b89\u5168\u6709\u6548\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u63a8\u8350\u5242\u91cf\u3011<\/p>\n<p>\u2022 \u5b8c\u5168\u6309\u7167\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\u7684\u65b9\u5f0f\u670d\u7528 LORLADX\u3002\u4e0d\u8981\u6539\u53d8\u5242\u91cf\u6216\u505c\u6b62\u670d\u7528 LORLADX\uff0c\u9664\u975e\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\u8fd9\u6837\u505a\u3002<\/p>\n<p>\u2022 \u5982\u679c\u60a8\u51fa\u73b0\u4e0d\u826f\u53cd\u5e94\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u4f1a\u6539\u53d8\u60a8\u7684\u5242\u91cf\u3001\u6682\u65f6\u505c\u6b62\u6216\u6c38\u4e45\u505c\u6b62\u4f7f\u7528 LORLADX \u8fdb\u884c\u6cbb\u7597\u3002<\/p>\n<p>\u2022 \u541e\u4e0b\u6574\u4e2a LORLADX \u836f\u7247\u3002\u4e0d\u8981\u5480\u56bc\u3001\u538b\u788e\u6216\u5206\u5f00 LORLADX \u7247\u5242\u3002\u5982\u679c\u836f\u7247\u4e2d\u65ad\u3001\u5206\u5f00\u6216\u4e0d\u5b8c\u6574\uff0c\u4e0d\u8981\u670d\u7528 LORLADX\u3002<\/p>\n<p>\u2022 \u6bcf\u5929\u51e0\u4e4e\u5728\u540c\u4e00\u65f6\u95f4\u670d\u7528LORLADX\u3002<\/p>\n<p>\u2022\u60a8\u53ef\u4ee5\u968f\u9910\u6216\u5355\u72ec\u670d\u7528LORLADX\u3002<\/p>\n<p>\u2022 \u5982\u679c\u60a8\u9519\u8fc7\u4e86\u914d\u836f\uff0c\u8bf7\u5728\u8bb0\u8d77\u65f6\u52a0\u5feb\u670d\u7528\u3002\u4f46\u662f\uff0c\u5982\u679c\u63a5\u8fd1\u60a8\u7684\u4e0b\u4e00\u6b21\u670d\u836f\u65f6\u95f4\uff08\u57284\u5c0f\u65f6\u5185\uff09\uff0c\u53ea\u9700\u5728\u60a8\u7684\u5e38\u89c4\u65f6\u95f4\u670d\u7528\u4e0b\u4e00\u6b21\u5373\u53ef\u3002<\/p>\n<p>\u2022 \u5982\u679c\u60a8\u5728\u5455\u5410\u540e\u670d\u7528\u4e00\u79cd\u836f\u7269LORLADX\uff0c\u8bf7\u989d\u5916\u670d\u7528\u3002\u5728\u60a8\u7684\u5e38\u89c4\u65f6\u95f4\u5185\u670d\u7528\u4e0b\u4e00\u79cd\u836f\u7269\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u3010\u9644\u5e26\u3011<\/p>\n<p>\u2022 \u7531\u4e8e\u4e0e\u5176\u4ed6\u836f\u7269\u7684\u53cd\u5e94\u800c\u5bfc\u81f4\u7684\u5fc3\u810f\u75c5\u95ee\u9898\u3002\u4e86\u89e3\u54ea\u4e9b\u836f\u7269\u4e0d\u5b9c\u4e0e LORLADX \u4e00\u8d77\u670d\u7528\u975e\u5e38\u91cd\u8981\u3002<\/p>\n<p>\u2022 \u5927\u8111\uff08\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf [CNS]\uff09\u529f\u80fd\u51fa\u73b0\u95ee\u9898\u3002 \u8bb8\u591a\u60a3\u8005\u5728\u4f7f\u7528 LORLADX \u6cbb\u7597\u671f\u95f4\u90fd\u7ecf\u5386\u4e86\u529f\u80fd\u95ee\u9898\uff0c\u5305\u62ec\u601d\u7ef4\u95ee\u9898\uff08\u5982\u5065\u58ee\u6216\u5065\u5fd8\u75c7\uff09\u3001\u60c5\u7eea\u95ee\u9898\uff08\u5982\u6291\u90c1\u75c7\uff09\u3001\u8a00\u8bed\u3001\u770b\u89c1\u6216\u542c\u5230\u4e0d\u771f\u5b9e\u7684\u4e8b\u60c5\uff08\u5e7b\u89c9\uff09\u4ee5\u53ca\u53cd\u9988\u3002 \u5728\u67d0\u4e9b\u60a3\u8005\u4e2d\uff0c\u8fd9\u4e9b\u95ee\u9898\u975e\u5e38\u4e25\u91cd\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u9700\u8981\u505c\u6b62\u670d\u7528 LORLADX\u3002<\/p>\n<p>\u2022 \u8840\u6db2\u4e2d\u80c6\u56fa\u9187\u548c\u7518\u6cb9\u4e09\u916f\uff08\u8c03\u8282\uff09\u6c34\u5e73\u5347\u9ad8\u3002\u5927\u591a\u6570\u60a3\u8005\u5728\u4f7f\u7528 LORLADX \u6cbb\u7597\u671f\u95f4\u8840\u6db2\u4e2d\u8c03\u8282\u6c34\u5e73\u4f1a\u5347\u9ad8\u3002<\/p>\n<p>\u5982\u679c\u60a8\u5728\u4f7f\u7528 LORLADX \u6cbb\u7597\u671f\u95f4\u8840\u6db2\u4e2d\u7684\u7535\u4f4d\u5347\u9ad8\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u9700\u8981\u5f00\u59cb\u4f7f\u7528\u836f\u7269\u6765\u964d\u4f4e\u6c34\u5e73\u3002 \u5982\u679c\u60a8\u5df2\u7ecf\u5728\u670d\u7528\u836f\u7269\u6765\u964d\u4f4e\u8840\u6db2\u4e2d\u7684\u7535\u4f4d\u6c34\u5e73\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u9700\u8981\u5f00\u59cb\u4f7f\u7528\u836f\u7269\u6765\u964d\u4f4e\u8840\u6db2\u4e2d\u7684\u7535\u4f4d\u6c34\u5e73\u3002\u63d0\u4f9b\u8005\u53ef\u80fd\u9700\u8981\u589e\u52a0\u8be5\u836f\u7269\u7684\u5242\u91cf\u3002<\/p>\n<p>\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u5e94\u5728\u5f00\u59cb\u6cbb\u7597\u524d\u3001\u5f00\u59cb\u6cbb\u7597\u540e 1 \u81f3 2 \u4e2a\u6708\u4ee5\u53ca\u4f7f\u7528 LORLADX \u6cbb\u7597\u671f\u95f4\u8fdb\u884c\u8840\u6db2\u68c0\u67e5\uff0c\u4ee5\u68c0\u67e5\u8840\u6db2\u4e2d\u7684\u78b1\u5ea6\u6c34\u5e73\u3002<\/p>\n<p>\u2022 \u5fc3\u810f\u95ee\u9898\u3002 LORLADX \u53ef\u80fd\u5bfc\u81f4\u5fc3\u7387\u975e\u5e38\u7f13\u6162\u6216\u5f02\u5e38\u3002 \u5728\u5f00\u59cb\u4f7f\u7528 LORLADX \u4e4b\u524d\u548c\u6cbb\u7597\u671f\u95f4\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u5e94\u68c0\u67e5\u60a8\u7684\u5fc3\u5f8b\uff08\u5fc3\u7535\u56fe [EKG]\uff09\u3002 \u5982\u679c\u60a8\u611f\u5230\u5934\u6655\u3001\u660f\u53a5\u6216\u5fc3\u8df3\u5f02\u5e38\uff0c\u8bf7\u7acb\u5373\u544a\u8bc9\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u3002\u67d0\u4e9b\u5728\u60a3\u8005\u4e2d\uff0c\u8fd9\u4e9b\u95ee\u9898\u975e\u5e38\u4e25\u91cd\uff0c\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u53ef\u80fd\u9700\u8981\u8ba9\u60a8\u505c\u6b62\u670d\u7528 LORLADX \u6216\u653e\u7f6e\u5fc3\u810f\u8d77\u8df3\u5668\u3002<\/p>\n<p>\u2022 \u80ba\u90e8\u95ee\u9898\u3002 LORLADX \u53ef\u80fd\u4f1a\u5728\u6cbb\u7597\u671f\u95f4\u5f15\u8d77\u4e25\u91cd\u6216\u5371\u53ca\u751f\u547d\u7684\u80ba\u90e8\u80bf\u7624\uff08\u80f0\u817a\uff09\uff0c\u4ece\u800c\u5bfc\u81f4\u6b7b\u4ea1\u3002 \u75c7\u72b6\u53ef\u80fd\u4e0e\u80ba\u764c\u76f8\u4f3c\u3002 \u5982\u679c\u60a8\u6709\u4efb\u4f55\u65b0\u7684\u6216\u6076\u5316\u7684\u80ba\u90e8\u95ee\u9898\u75c7\u72b6\uff0c\u5305\u62ec\u547c\u5438\u547c\u5438\u56f0\u96be\u3001\u547c\u5438\u6025\u4fc3\u3001\u54b3\u55fd\u6216\u53d1\u70e7\uff0c\u8bf7\u7acb\u5373\u544a\u8bc9\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u3002<\/p>\n<p>\u2022 \u5b8c\u5168\u6309\u7167\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\u7684\u65b9\u5f0f\u670d\u7528 LORLADX\u3002\u9664\u975e\u60a8\u7684\u533b\u7597\u4fdd\u5065\u63d0\u4f9b\u8005\u544a\u8bc9\u60a8\uff0c\u5426\u5219\u4e0d\u8981\u6539\u53d8\u60a8\u7684\u5242\u91cf\u6216\u505c\u6b62\u670d\u7528 LORLADX\u3002<\/p>\n<p>\u2022 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