泰吉华/阿伐替尼 LuciAvap是一种激酶抑制剂，适用于： 1、胃肠道间质瘤：治疗携带血小板衍生生长因子受体α（PDGFRA）外显子18突变（包括PDGFRA D842V突变）的不可切除或转移性GIST成年人。

Avapritinib is an oral tyrosine kinase inhibitor used primarily to treat a rare gastrointestinal tumor called gastrointestinal stromal tumor (GIST).

Indications

Afatinib is approved for the treatment of patients with unresectable or metastatic gastrointestinal stromal tumors (GIST) with specific mutation types, such as the PDGFRA D842V mutation.

Dosage

The dosage of afatinib should be determined by the doctor according to the patient's specific condition. Generally, the recommended dosage for adults is once daily orally, and the dosage may be adjusted based on tolerance and efficacy. The specific method of use should follow the doctor's guidance.

Adverse Reactions

Common adverse reactions include:

• Blood system : may cause anemia, leukopenia and thrombocytopenia, etc.

• Nervous system : Headache, dizziness, visual impairment, etc. may occur.

• Digestive system : Nausea, vomiting, diarrhea, etc. may occur.

• Skin : Rash, dryness, etc. may occur.

Serious adverse reactions may include bleeding, heart problems, etc. If serious adverse reactions occur, you should contact your doctor immediately.

Precautions

• Hematological monitoring : During treatment, blood routine examinations should be performed regularly to monitor blood cell counts and promptly detect and deal with adverse reactions to the blood system.

• Neurological monitoring : If neurological symptoms such as visual disturbances occur, they should be reported to the doctor promptly.

• Pregnant and lactating women : Afatinib may cause harm to the fetus and should be avoided by pregnant women; lactating women should stop breastfeeding when using it.

Contraindications

• Patients with hypersensitivity to afatinib or any of its ingredients : Contraindicated.

• Pregnant and lactating women : Do not use.

Drug interactions

Afatinib may interact with other drugs, affecting efficacy or increasing the risk of adverse reactions. Before starting a new medication, you should consult your doctor or pharmacist.

Storage conditions

This product should be stored below 25°C away from moisture and direct sunlight.

Please read the drug instructions carefully before use and follow the doctor's instructions for treatment.